Substance Abuse and Addiction in Males: Gender and Development Matters. Educating Boys and Men about Substance Abuse and the Developing Brain. Male Socialization, Substance Abuse, and Self-Regulation. Substance Abuse Counseling with Early Adolescent Males (12 to 18). Substance Abuse Counseling with Late Adolescent Males (18 to 24). Substance Abuse Counseling with Males in Early Adulthood (24 to 34). Substance Abuse Counseling with Males in Middle Adulthood (34 to 60). Substance Abuse Counseling with Older Adult Males (60 and above).