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Critical Care Management for Laboratory Mice and Rats

By F. Claire Hankenson

CRC Press – 2013 – 271 pages

Series: Laboratory Animal Pocket Reference

Purchasing Options:

  • Add to CartPaperback: $59.95
    978-0-8493-2499-4
    October 2nd 2013

Description

For critical care of laboratory rodents, there is a scarcity of sources for comprehensive, feasible, and response-oriented information on clinical interventions specific to spontaneous and induced models of disease. With the more complex cases that need critical care management, many treatment approaches to veterinary emergencies cannot be applied directly to the laboratory rodent. The first text of its kind devoted to the challenges of critical care management for laboratory rodents, Critical Care Management for Laboratory Mice and Rats provides a specialized resource for all veterinary, husbandry, technical, and research professionals who utilize rodent models for biomedical research.

The book covers the varied approaches to laboratory rodent patient care, health assessments, characteristics of specific disease models, monitoring and scoring of disease parameters, and humane interventions. Giving primary consideration to preservation of animal health and welfare, the text also considers how best to balance welfare with the achievement of proposed scientific objectives. Organized into five chapters, this full-color book covers the following topics:

  • General Approaches for Critical Care
  • Critical Care Management for Laboratory Mice
  • Critical Care Management for Laboratory Rats
  • Special Considerations for Critical Care Management in Laboratory Rodents
  • Resources and Additional Information

The author provides treatment guidelines with the expectation that they will be applied with apt professional judgment, allowing for further modification of clinical recommendations for improved patient-based care and welfare for research animals.

Contents

general approaches for critical care

overview

obtaining a clinical history and medical records

body condition scoring

relocation for physical examinations

monitoring critically ill rodents

pain recognition and assessments

supportive care for surgical procedures

supplemental heat provision

drug therapy

references

critical care management for laboratory mice

introduction

overall assessments

general medical approaches to physical examination and health assessments

veterinary care measures

abnormal, critical, and emergent conditions

research-related medical issues

euthanasia

references

critical care management for laboratory rats

introduction

overall assessments

general medical approaches to physical examination and health assessments

veterinary care measures

abnormal, critical, and emergent conditions

research-related medical issues

euthanasia

references

special considerations for critical care management in laboratory rodents

introduction

aging animal model considerations

blood loss considerations

chronic indwelling device considerations

depilatory cream considerations

equipment considerations for rodent surgery

and emergency procedures

euthanasia considerations

experimental autoimmune encephalomyelitis and demyelinating disease model considerations

fasting considerations

fluid therapy considerations

food and fluid regulation procedures

humane or "clinical" endpoint considerations

nutritional therapy considerations

perioperative care considerations

regulatory considerations

restraint collar considerations

tracheostomy considerations

tumor development and monitoring considerations

wound management considerations

references

resources and additional information

introduction

organizations

publications

electronic resources

commercial resources

appendix A: glossary of acronyms and terms

appendix B: suggested medical supplies for rodent

critical care

appendix C: rodent formulary

Index

Author Bio

F. Claire Hankenson, DVM, MS, is the senior associate director in University Laboratory Animal Resources, University of Pennsylvania, Philadelphia, and is an associate professor of laboratory animal medicine in the Department of Pathobiology at the School of Veterinary Medicine. Dr. Hankenson obtained her veterinary degree from Purdue University. Following veterinary school, she completed her laboratory animal medicine residency and graduate work (MS, microbiology) at the University of Washington, Seattle. She became a Diplomate of the American College of Laboratory Animal Medicine (ACLAM) in 2002. Her own research studies involve investigations of refinements in the care and use of laboratory rodents, particularly blood sampling, tail biopsy evaluations, and humane endpoints.

Name: Critical Care Management for Laboratory Mice and Rats (Paperback)CRC Press 
Description: By F. Claire Hankenson. For critical care of laboratory rodents, there is a scarcity of sources for comprehensive, feasible, and response-oriented information on clinical interventions specific to spontaneous and induced models of disease. With the more complex cases that need...
Categories: Laboratory Animal Science, Animal Physiology, Toxicology