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Statistics of Medical Imaging

By Tianhu Lei

Published December 19th 2011 by Chapman and Hall/CRC – 438 pages

Series: Chapman & Hall/CRC Interdisciplinary Statistics

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Description

Statistical investigation into technology not only provides a better understanding of the intrinsic features of the technology (analysis), but also leads to an improved design of the technology (synthesis). Physical principles and mathematical procedures of medical imaging technologies have been extensively studied during past decades. However, less work has been done on their statistical aspect. Filling this gap, this book provides a theoretical framework for statistical investigation into medical technologies. Rather than offer detailed descriptions of statistics of basic imaging protocols of X-ray CT and MRI, the book presents a method to conduct similar statistical investigations into more complicated imaging protocols.

Reviews

"Statistics of Medical Imaging is an in-depth and mathematical account of the statistics associated with medical imaging technologies, particularly x-ray CT and MR imaging. The text is logically structured into a review of mathematics and imaging principles, and then it transitions to describing the statistics of CT and MR imaging and images and image analysis models. … the text is successful at developing a structured argument for the statistical properties with supporting background physics, mathematical proofs, and integrated statistical models for both x-ray CT and MRI."

—Camille Palmer, Health Physics-The Radiation Protection Journal, March 2013

"This is a good reference for graduate students and researchers in signal processing and electrical and systems engineering. … The author has demonstrated a mastery and thorough knowledge of this subject and has done a superb job of describing CT and MR image and imaging statistics systematically. The book is unique in the targeted signal processing literature, rationally illustrating the steps of analyzing CT and MR images statistically and providing an evaluation tool. The equation derivations are written in a rigorous way so that researchers and students in signal processing can understand the basic principles. With some background knowledge, researchers can also perform statistical analysis and evaluate the statistics on CT and MR images and imaging processes."

—Teh Lin, Doody’s Review Service, 2013

Contents

Introduction

Data Flow and Statistics

Imaging and Image Statistics

Statistical Image Analysis

Motivation and Organization

X-ray CT Physics and Mathematics

Introduction

Photon Emission, Attenuation, and Detection

Attenuation Coefficient

Projections

Mathematical Foundation of Image Reconstruction

Fourier Slice theorem

Image Reconstruction

MRI Physics and Mathematics

Introduction

Nuclear Spin and Magnetic Moment

Alignment and Precession

Macroscopic Magnetization

Resonance and Relaxation

Bloch Equation and Its Solution

Excitation

Induction

k-Space and k-Space Sample

Image Reconstruction

Echo Signal

Non-diffraction Computed Tomography

Introduction

Interaction between EM Wave and Object

Inverse Scattering Problem

Non-diffraction Computed Tomography

Statistics of X-ray CT Imaging

Introduction

Statistics of Photon Measurements

Statistics of Projections

Statistical Interpretation of X-ray CT Image Reconstruction

Statistics of X-ray CT Image

Introduction

Statistics of the Intensity of a Single Pixel

Statistics of the Intensities of Two Pixels

Statistics of the Intensities of a Group of Pixels

Statistics of MR Imaging

Introduction

Statistics of Macroscopic Magnetizations

Statistics of MR Signals

Statistics of k-Space Samples

Statistical Interpretation of MR Image Reconstruction

Statistics of MR Image

Introduction

Statistics of the Intensity of a Single Pixel

Statistics of the Intensities of Two Pixels

Statistics of the Intensities of a Group of Pixels

Discussion and Remarks

Stochastic Image Models

Introduction

Stochastic Model I

Stochastic Model II

Discussion

Statistical Image Analysis – I

Introduction

Detection of Number of Image Regions

Estimation of Image Parameters

Classification of Pixels

Statistical Image Analysis

Statistical Image Analysis – II

Introduction

Detection of the Number of Image Regions

Estimation of Image Parameters

Classification of Pixels

Statistical Image Analysis

Performance Evaluation of Image Analysis Methods

Introduction

Performance of the iFNM Model-Based Image Analysis Method

Performance of the cFNM Model-Based Image Analysis Method

Index

Author Bio

Tianhu Lei is an associate professor at the University of Pittsburgh. He has previously worked at the University of Maryland, the University of Pennsylvania, and the Children’s Hospital of Philadelphia. He earned a Ph.D. in electric and system engineering from the University of Pennsylvania.

Name: Statistics of Medical Imaging (Hardback)Chapman and Hall/CRC 
Description: By Tianhu Lei. Statistical investigation into technology not only provides a better understanding of the intrinsic features of the technology (analysis), but also leads to an improved design of the technology (synthesis). Physical principles and mathematical procedures...
Categories: Statistics for the Biological Sciences, Biomedical Engineering, Image Processing