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The Laboratory Zebrafish

By Claudia Harper, Christian Lawrence

CRC Press – 2010 – 274 pages

Series: Laboratory Animal Pocket Reference

Purchasing Options:

  • Add to CartPaperback: $59.95
    978-1-43-980743-9
    December 16th 2010

Description

Like other books in the Laboratory Animal Pocket Reference Series, this guide covers all aspects pertaining to the use of these organisms including their basic biology, humane care and management, husbandry, life support systems, regulatory compliance, technical procedures, veterinary care, and water quality management.

In the relatively brief span of only a few decades, the zebrafish has gone from being mainly a hobby fish to a mainstream model animal employed by scientists to study everything from stem cells to the basis of behavioral changes induced by drug addiction. This rapid advance has been fueled largely by numerous and impressive advances in technology, along with detailed characterization of the animal on a genetic and molecular level. These developments have allowed scientists to leverage the many advantages of the zebrafish system to address many important questions in biology and human genetics and disease.

However, there are few accepted and established standards for husbandry, management, and care for the fish in laboratory settings and even fewer comprehensive and constantly reliable resources. To this end, the goal of this handbook is to provide managers, veterinarians, investigators, technicians, and regulatory personnel with a concise yet thorough reference on zebrafish biology, care, husbandry, and management.

The aim of the book is not to set standards, but rather to arm those working with the fish with scientifically grounded principles and fundamental information that can be used to design sound fish care programs. This handbook is organized into seven chapters:

Biology

Husbandry

Life Support Systems

Management

Veterinary Care

Experimental Methodology

Resources

The final chapter, Resources, provides the zebrafish user with lists of sources of additional information on the zebrafish model, as well as key references, professional organizations, and suppliers of equipment and supplies used in zebrafish husbandry and care.

Contents

BIOLOGY

INTRODUCTION

NATURAL HISTORY

GENETICS

GENETIC STRAINS

NOMENCLATURE

BEHAVIOR

ANATOMY AND PHYSIOLOGY

CLINICAL CHEMISTRY AND HEMATOLOGY

HUSBANDRY

NUTRITION AND FEEDING

BREEDING

LARVICULTURE

HOUSING DENSITY

GENETIC MANAGEMENT

IDENTIFICATION AND RECORD KEEPING

TRANSPORTATION

LIFE SUPPORT

FACILITY DESIGN

HOUSING SYSTEMS

WATER SOURCE

WATER QUALITY MANAGEMENT

EFFLUENT MANAGEMENT

MANAGEMENT

REGULATORY AGENCIES AND COMPLIANCE

INSTITUTIONAL ANIMAL CARE AND USE COMMITTEES

OCCUPATIONAL HEALTH AND ZOONOTIC DISEASES

DISPOSITION OF FISH

VETERINARY CARE

BASIC BIOLOGIC PARAMETERS

ANIMAL WELFARE INDICATORS FOR FISH

STRESS RESPONSE IN FISH

CLINICAL CASE MANAGEMENT AND SAMPLE COLLECTION

COMMON DISEASES OF THE LABORATORY ZEBRAFISH

PREVENTIVE MEDICINE

HEALTH SURVEILLANCE AND MONITORING

ANESTHESIA AND EUTHANASIA

EXPERIMENTAL METHODOLOGY

RESTRAINT

SAMPLING METHODS

COMPOUND ADMINISTRATION

SURGICAL PROCEDURES

RESOURCES

ORGANIZATIONS

PUBLICATIONS

ELECTRONIC RESOURCES

EQUIPMENT AND SUPPLIES

APPENDIX 1.

SAMPLE ARTEMIA DECAPSULATION SOP

APPENDIX 2.

SAMPLE ZEBRAFISH FACILITY CHECKSHEET

BIBLIOGRAPHY

INDEX

Name: The Laboratory Zebrafish (Paperback)CRC Press 
Description: By Claudia Harper, Christian Lawrence. Like other books in the Laboratory Animal Pocket Reference Series, this guide covers all aspects pertaining to the use of these organisms including their basic biology, humane care and management, husbandry, life support systems, regulatory compliance,...
Categories: Developmental Biology, Neuroscience, Laboratory Animal Science