Monte Carlo Techniques in Radiation Therapy
Edited by Joao Seco, Frank Verhaegen
CRC Press – 2013 – 342 pages
Modern cancer treatment relies on Monte Carlo simulations to help radiotherapists and clinical physicists better understand and compute radiation dose from imaging devices as well as exploit four-dimensional imaging data. With Monte Carlo-based treatment planning tools now available from commercial vendors, a complete transition to Monte Carlo-based dose calculation methods in radiotherapy could likely take place in the next decade. Monte Carlo Techniques in Radiation Therapy explores the use of Monte Carlo methods for modeling various features of internal and external radiation sources, including light ion beams.
The book—the first of its kind—addresses applications of the Monte Carlo particle transport simulation technique in radiation therapy, mainly focusing on external beam radiotherapy and brachytherapy. It presents the mathematical and technical aspects of the methods in particle transport simulations. The book also discusses the modeling of medical linacs and other irradiation devices; issues specific to electron, photon, and proton ion beams and brachytherapy; and the optimization of treatment planning, radiation dosimetry, and quality assurance.
Useful to clinical physicists, graduate students, and researchers, this book provides a detailed, state-of-the-art guide to the fundamentals, application, and customization of Monte Carlo techniques in radiotherapy. Through real-world examples, it illustrates the use of Monte Carlo modeling and simulations in dose calculation, beam delivery, kilovoltage and megavoltage imaging, proton radiography, device design, and much more.
"… this is the first textbook targeted at medical physicists that provides not only explanations of the fundamentals of MC methodology, but also reviews the application of this calculation methodology in a variety of RT fields. … This textbook and the foundation chapters in particular should be considered an essential resource for any student or practitioner of MC techniques in RT."
—Australasian Physical and Engineering Sciences in Medicine, March 2014
Monte Carlo Fundamentals
History of Monte Carlo
Alex F. Bielajew
Basics of Monte Carlo Simulations
Variance Reduction Techniques
Application of Monte Carlo Techniques in Radiation Therapy
Applications of Monte Carlo to Radiation Dosimetry
Hugo Bouchard and Jan Seuntjens
Monte Carlo Modeling of External Photon Beams in Radiotherapy
Monte Carlo Modeling of External Electron Beams in Radiotherapy
Dynamic Beam Delivery and 4D Monte Carlo
Emily Heath and Joao Seco
Patient Dose Calculation
Joao Seco and Maggy Fragoso
Monte Carlo Methods and Applications for Brachytherapy Dosimetry and Treatment Planning
Guillaume Landry, Mark R. Rivard, Jeffrey F. Williamson, and Frank Verhaegen
Monte Carlo as a QA Tool for Advanced Radiation Therapy
JinSheng Li and C.-M. Charlie Ma
Electrons: Clinical Considerations and Applications
Joanna E. Cygler and George X. Ding
Photons: Clinical Considerations and Applications
Michael K. Fix
Monte Carlo Calculations for Proton and Ion Beam Dosimetry
Protons: Clinical Considerations and Applications
Application of Monte Carlo Methods to Radionuclide Therapy
Monte Carlo for Kilovoltage and Megavoltage Imaging
George X. Ding and Andrew Fielding
Monte Carlo Calculations for PET-Based Treatment Verification of Ion Beam Therapy
Monte Carlo Studies of Prompt Gamma Emission and of Proton Radiography/Proton-CT
Joao Seco, Jerimy C. Polf, and Katia Parodi
Monte Carlo for Treatment Device Design
Bruce A. Faddegon
GPU-Based Fast Monte Carlo Simulation for Radiotherapy Dose Calculation
Xun Jia, Sami Hissoiny, and Steve B. Jiang
Monte Carlo for Shielding of Radiotherapy Facilities
Peter J. Biggs and Stephen F. Kry
Joao Seco is an assistant professor of radiation oncology at Harvard Medical School and Massachusetts General Hospital. He earned his PhD from the Institute of Cancer Research, University of London. His research interests range from proton imaging and therapy to photon beam modeling Monte Carlo, electronic portal imaging, and 4D Monte Carlo proton and photon dosimetry.
Frank Verhaegen is head of clinical physics research at the Maastro Clinic. He also holds a professorship at the University of Maastricht. Dr. Verhaegen is a fellow of the Institute of Physics and Engineering in Medicine and the Institute of Physics. He earned his PhD from the University of Ghent. His research interests include imaging and dosimetry for photon and electron therapy, brachytherapy, particle therapy, and small animal radiotherapy.