Chemistry of Natural Products
Sources, Separations and Structures
By George Nicola, Raymond Cooper
To Be Published February 15th 2014 by CRC Press – 400 pages
Description
Compounds isolated from nature have long been known to possess biological profiles and pharmaceutical potential far greater than anything made by man. However, they are notoriously cumbersome to isolate and challenging to synthesize, and the path of natural products to viable drugs is an arduous journey. This book presents a practical guide to gathering, isolating, and discovering new pharmaceuticals from nature. It emphasizes the challenges and advantages of products acquired from nature over traditional compounds such as those arising from combinatorial chemistry.
Contents
History of Natural Products
Terrestrial
Marine
Bioprospecting
Biological and Pharmacological Aspects
Fractionation and Isolation
Structure Elucidation
X-ray crystallography
NMR
Mass Spectrometry
Biosynthesis
Chemical Synthesis
Optimization for Mass Production and Manufacturing
Medicinal Applications
Integrating with System Biology
Computational Chemistry
Sustainability
Biopiracy
Environmental Protection
International Treaties
Translation
Curation and Digitization
Intellectual Property
Licensing and Strategy
Related Subjects
Name: Chemistry of Natural Products: Sources, Separations and Structures (Paperback) – CRC Press
Description: By George Nicola, Raymond Cooper. Compounds isolated from nature have long been known to possess biological profiles and pharmaceutical potential far greater than anything made by man. However, they are notoriously cumbersome to isolate and challenging to synthesize, and the path of...
Categories: Natural Products, Medicinal & Pharmaceutical Chemistry, Pharmacology