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Melatonin

Therapeutic Value and Neuroprotection

Edited by Venkatramanujan Srinivasan, Gabriella Gobbi, Samuel D. Shillcutt, Sibel Suzen

CRC Press – 2014 – 580 pages

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  • Pre-Order NowHardback: $199.95
    978-1-48-222009-4
    September 19th 2014
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Description

There is a growing interest in the field of melatonin research concerning its neurobiological mechanisms as well as its repercussions in clinical practice. A decrease in melatonin production and receptors results in numerous dysfunctions in the body. This text explores melatonin’s neuroprotective effects and discusses the therapeutic potential of melatonin and melatonin agonists in treating neurodegenerative diseases. In addition to addressing the neuroprotective role of melatonin, the book also explores its protective roles in other tissues such as the brain, heart, and liver.

Contents

Neuroprotective role of melatonin in neurodegenerative diseases

Melatonin: pharmacological and clinical aspects

MT2 Melatonin receptors: Their role in sleep and neuropsychiatric disorders

Melatonin and synthetic analogs as antioxidants

Melatonin in ageing and diseases

Melatonin’s mitochondrial protective role in Alzheimer’s disease

Regulation of adult hippocampal neurogenesis by melatonin

Melatonin and melatonergic drugs in oxidative stress of hippocampal neurons of transgenic model of Alzheimer’s Disease

Melatonin’s neuroprotective actions on hippocampus

Neuroprotective agents in Parkinson disease models

Neuroprotective actions of melatonin in hemiparkinsonian model

Melatonin and nimodipine: their therapeutic use for cerebral cortical injury

Melatonin’s protection against human prion mediated neurotoxicity

Neuroprotective role of melatonin in glaucoma

Melatonin analogues in glaucoma: therapeutic implications

Melatonin: Its cardioprotective role

Melatonin: Its hepato protective actions and the role of melatonin receptors

Melatonin receptors and their preventive role in carcinogenesis: molecular pathways

Melatonin as a natural programmed cell death inducer in cancer

Melatonin use in hepatic injury and its beneficial effects

Melatonin for treatment of sepsis: current status

Melatonin’s protective effects against radiation induced nephrotoxicity

Melatonin in metabolic syndrome: beneficial effects

Melatonin and its atheroprotective effects

Melatonin’s protective action against non-steroidal anti-inflammatory drugs

Melatonin and urosolic acid in colon cancer

Melatonin’s protection against metamphetamine toxicity in human neuroblastoma cells

Melatonin’s antiapoptotic activity in neurodegenerative diseases

Neuroprotective role of melatonin and acetyl-L- carnitine against dexamethasone induced toxicity

Melatonin and peripheral nerve regeneration

Melatonin’s histological actions in experimental models

Neuroprotective effects of melatonin in hypoxic conditions

Melatonergic modulation and circadian rhythmicity in bipolar disorders

Neuroprotection by cyclodextrin in animal models of Alzheimer’s disease

Neuroprotection against rotenone toxicity

Neuroprotective role of phytochemicals

Melanocortins in CNS injury and repair

Melatonergic drug, ramelteon and its therapeutic applications

Name: Melatonin: Therapeutic Value and Neuroprotection (Hardback)CRC Press 
Description: Edited by Venkatramanujan Srinivasan, Gabriella Gobbi, Samuel D. Shillcutt, Sibel Suzen. There is a growing interest in the field of melatonin research concerning its neurobiological mechanisms as well as its repercussions in clinical practice. A decrease in melatonin production and receptors results in numerous dysfunctions in the body...
Categories: Neuroscience, Pharmacology, Endocrinology