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Description

How can environmental regulators use information on 48-hour toxicity tests to predict the effects of a few minutes of pollution? Or, at the other extreme, what is the relevance of 96-hour toxicity data for organisms that may have been exposed to a pollutant for six months or more? Time to event methods are the key to answering these types of questions.

Risk Assessment with Time to Event Models is the first comprehensive treatment of these methods in the context of ecological risk assessment. Leading experts from industry, academia, and government regulatory agencies explain how these methods can be used to extract more useful information from laboratory data than is present in simple summary statistics like 48-h LC50.

The book offers a clear introduction to the field through several approaches, from the introductory to the more mathematical. Risk Assessment with Time to Event Models demonstrates the relevance of time in the analysis and reporting of toxicity data through the use of practical examples from the field of environmental toxicology. It also incorporates helpful analogies from other disciplines that commonly use time to event modeling.

Contents

Introduction to Time to Event Methods, M.C. Newman and M. Crane

Time to Event Analysis of Standard Ecotoxicity Data, M. Crane and A. Grosso

Applying Time to Event Methods to Assess Pollutant Effects on Populations, M.C. Newman and J.T. McCloskey

Time-Concentration-Effect Models in Predicting Chronic Toxicity from Acute Toxicity Data, F.L. Mayer, M.R. Ellersieck, G.F. Krause, K. Sun, G. Lee, and D.R. Buckler

Just How Much Better is a Time to Event Analysis? P.M. Dixon

Using Time to Event Modelling to Assess the Ecological Risk of Produced Water Discharges, C.C. Karman

Time to Event Analysis in the Agricultural Sciences, J.S. Fenlon

Time to Event Analysis in Ecology, B.F. Manly

Time to Event Methods in Engineering, A. Kimber

Can Risk Assessment be Improved with Time to Event Models? M. Crane, P.F. Chapman, T. Sparks, J. Fenlon, and M.C. Newman

Conclusions, M. Crane, P.F. Chapman, and M.C. Newman

Name: Risk Assessment with Time to Event Models (Hardback)CRC Press 
Description: Edited by Mark Crane, Michael C. Newman, Peter F. Chapman, John S. FenlonContributors: Denny R. Buckler, Foster Lee Mayer, Philip M. Dixon, Gary F. Krause, Mark R. Ellersieck, Bryan F.J. Manly, Albania Grosso, Chris C. Karman, Alan Kimber, Jon McCloskey, Tim Sparks, Kai Sun, Gunhee Lee. How can environmental regulators use information on 48-hour toxicity tests to predict the effects of a few minutes of pollution? Or, at the other extreme, what is the relevance of 96-hour toxicity data for organisms that may have been exposed to a...
Categories: Natural Hazards & Risk, Environmental & Ecological Toxicology, Statistics