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Translational Medicine

The Future of Therapy?

Edited by James Mittra, Christopher-Paul Milne

Pan Stanford – 2013 – 294 pages

Purchasing Options:

  • Add to CartHardback: $149.95
    9789814316996
    April 16th 2013

Description

This book brings together a range of academic, industry and practitioner perspectives on translational medicine (TM). It enhances conceptual and practical understanding of the emergence and progress of the field and its potential impact on basic research, therapeutic development, and institutional infrastructure. In recognition of the various implications TM has for public health policy and commercial innovation, the book addresses the major systemic aspects of the field. The contributors explore the dynamic interactions and key challenges in translating new science into viable therapies for the clinic, which includes recognizing the importance of social, commercial, and regulatory environments in addition to good science.

Reviews

"This is a book that should be read by all those aiming to improve the efficiency and effectiveness of translation of science into clinical practice and health outcomes. Unlike other contributions in the field, it takes a holistic approach to the problem and recognises the dynamic nature of demand for as well as supply of health innovation, identifying strategies to integrate the two. This book has been needed for some time, but, with stagnating productivity and ever-increasing economic pressures, never more so than right now."

—Prof. Iain Gillespie, The University of Edinburgh, UK

Contents

Introduction

Introduction to Translational Medicine

James Mittra and Christopher-Paul Milne

Drivers and Barriers to Translational Medicine

New Light Through an Old Window? The "Translational Turn" in Biomedical Research — A Historical Perspective

Alison Kraft

Translational Medicine: The Industry Perspective

Christopher-Paul Milne, Christine Kohn

Drivers and Barriers of Translational Medicine: A Regulatory Perspective

Partha Roy, Atul Bhattaram, and Shiew Mei Huang

Developing an Evaluation Model for Translational Medicine Research Programs

Jim Jackson

State of the Art in Science and Technology

Emerging Concepts in Biomarker Discovery: Cancer Immunotherapy and Degenerative Diseases of the Eye as Model Systems

Robert B. Nussenblatt, and Francesco M. Marincola

Imaging Biomarkers for Innovative Drug Development: Translation from Bench to Bedside and Back

Jingsong Wang

Translational Bioinformatics: Bridging the Biological and Clinical Divide

Indra Neil Sarkar

Institutional Dynamics of Translational Medicine

Exploiting Translational Medicine Through Public–Private Partnerships: A Case Study of Scotland’s Translational Medicine Research Collaboration (TMRC)

James Mittra

The Role of the Product Development Partnership as a Translational Mechanism for Delivering Health Solutions in Low-Resource Settings

Julius Mugwagwa, Rebecca Hanlin, Joanna Chataway, and Lois Muraguri

Conclusions

Is Translational Medicine the Future of Therapy?

Christopher-Paul Milne and James Mittra

Author Bio

James Mittra is a research fellow and lecturer at the ESRC Innogen Centre and Science, Technology and Innovation Studies subject group at the University of Edinburgh. His research and teaching focuses on interdisciplinary approaches to the complex and dynamic ways in which life sciences are affecting the nature and the process of technological and therapeutic innovation within the pharmaceutical and biotechnology sectors. Dr. Mittra has published widely on issues of the strategic management and governance of the life sciences, as well as on mapping new value systems and business models for novel therapies.

Christopher-Paul Milne is director of research at the Tufts Center for the Study of Drug Development. His current research interests include academic–industry collaborations; disease, demographic, and market access factors in the emerging markets; incentive programs for pediatric studies, orphan products, and neglected diseases; and tracking the progress of new regulatory and research initiatives such as regulatory science, comparative effectiveness research, translational medicine, and personalized medicine. Dr. Milne is also research assistant professor at Tufts University Medical School, member of the editorial board of the Food & Drug Law Journal, and an honorary fellow at the University of Edinburgh.

Name: Translational Medicine: The Future of Therapy? (Hardback)Pan Stanford 
Description: Edited by James Mittra, Christopher-Paul Milne. This book brings together a range of academic, industry and practitioner perspectives on translational medicine (TM). It enhances conceptual and practical understanding of the emergence and progress of the field and its potential impact on basic...
Categories: Medicine, Bioinformatics, Drug Discovery