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  1. Group Sequential Methods with Applications to Clinical Trials

    By Christopher Jennison, Bruce W. Turnbull

    Series: Chapman & Hall/CRC Interdisciplinary Statistics

    Group sequential methods answer the needs of clinical trial monitoring committees who must assess the data available at an interim analysis. These interim results may provide grounds for terminating the study-effectively reducing costs-or may benefit the general patient population by allowing early...

    Published September 14th 1999 by Chapman and Hall/CRC

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