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1-9 of 9 results for Author: mark chang (sorted by Publication Date, showing all)
  1. Clinical Trial Simulations

    By Sandeep M. Menon, Mark Chang, Joseph M.W. Wu

    Series: Chapman & Hall/CRC Biostatistics Series

    In biopharmaceutical statistics, simulation plays an indispensable role. Statisticians conduct simulation studies to thoroughly characterize different statistical methodologies and to compare their performance in terms of type I error, power, sample sizes, etc. This book offers programming codes (...

    To Be Published December 26th 2015 by CRC Press

  2. Introductory Adaptive Trial Designs

    A Practical Guide with R

    By Mark Chang

    Series: Chapman & Hall/CRC Biostatistics Series

    All the Essentials to Start Using Adaptive Designs in No Time Compared to traditional clinical trial designs, adaptive designs often lead to increased success rates in drug development at reduced costs and time. Introductory Adaptive Trial Designs: A Practical Guide with R motivates newcomers to...

    To Be Published July 1st 2015 by Chapman and Hall/CRC

  3. Adaptive Design Theory and Implementation Using SAS and R, Second Edition

    By Mark Chang

    Series: Chapman & Hall/CRC Biostatistics Series

    Get Up to Speed on Many Types of Adaptive Designs Since the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials. Incorporating many of these new developments, Adaptive Design Theory and Implementation Using SAS and R, Second...

    Published December 1st 2014 by Chapman and Hall/CRC

  4. Principles of Scientific Methods

    By Mark Chang

    Principles of Scientific Methods focuses on the fundamental principles behind scientific methods. The book refers to "science" in a broad sense, including natural science, physics, mathematics, statistics, social science, political science, and engineering science. A principle is often abstract and...

    Published July 22nd 2014 by Chapman and Hall/CRC

  5. Clinical and Statistical Considerations in Personalized Medicine

    Edited by Claudio Carini, Sandeep M Menon, Mark Chang

    Series: Chapman & Hall/CRC Biostatistics Series

    The Future of Clinical Research and Health Care: From Empirical to Precision MedicineClinical and Statistical Considerations in Personalized Medicine explores recent advances related to biomarkers and their translation into clinical development. Leading clinicians, biostatisticians, regulators,...

    Published March 27th 2014 by Chapman and Hall/CRC

  6. Paradoxes in Scientific Inference

    By Mark Chang

    Paradoxes are poems of science and philosophy that collectively allow us to address broad multidisciplinary issues within a microcosm. A true paradox is a source of creativity and a concise expression that delivers a profound idea and provokes a wild and endless imagination. The study of paradoxes...

    Published October 15th 2012 by Chapman and Hall/CRC

  7. Adaptive Design Methods in Clinical Trials, Second Edition

    By Shein-Chung Chow, Mark Chang

    Series: Chapman & Hall/CRC Biostatistics Series

    With new statistical and scientific issues arising in adaptive clinical trial design, including the U.S. FDA’s recent draft guidance, a new edition of one of the first books on the topic is needed. Adaptive Design Methods in Clinical Trials, Second Edition reflects recent developments and...

    Published December 1st 2011 by Chapman and Hall/CRC

  8. Monte Carlo Simulation for the Pharmaceutical Industry

    Concepts, Algorithms, and Case Studies

    By Mark Chang

    Series: Chapman & Hall/CRC Biostatistics Series

    Helping you become a creative, logical thinker and skillful "simulator," Monte Carlo Simulation for the Pharmaceutical Industry: Concepts, Algorithms, and Case Studies provides broad coverage of the entire drug development process, from drug discovery to preclinical and clinical trial aspects to...

    Published September 29th 2010 by CRC Press

  9. Measuring Slipperiness

    Human Locomotion and Surface Factors

    Edited by Wen-Ruey Chang, Theodore K. Courtney, Raoul Grongvist, Mark Redfern

    In recent decades, injury has begun to gain prominence as a public health and societal problem. Slipperiness and slip, trip, and fall (STF) injuries are among the greatest obstacles to reducing the injury burden. One of the biggest challenges in STF is defining and measuring slipperiness. After...

    Published December 19th 2002 by CRC Press

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