New and Published Books
1-7 of 7 results in Critical Reviews in Combinatorial Chemistry
Since the publication of the benchmark first edition of this book, chemical library and combinatorial chemistry methods have developed into mature technologies. There have also been significant shifts in emphasis in combinatorial synthesis. Reflecting the growth in the field and the heightened...
Published August 8th 2010 by CRC Press
The development of suitable assays, the integration of appropriate technology, and the effective management of the essential infrastructure are all critical to the success of any high-throughput screening (HTS) endeavor. However, few scientists have the multidisciplinary experience needed to...
Published December 20th 2009 by CRC Press
The introduction of combinatorial chemistry technology has increased the amount of compounds generated in a year from 50 to 2000. Conventional analytical approaches simply cannot keep up. These circumstances have caused drug discovery to take on the shape of a bottleneck, like traffic through a...
Published August 19th 2008 by CRC Press
A Single Source on Parallel Synthesis for Lead Optimization The end of the previous millennium saw an explosion in the application of parallel synthesis techniques for making compounds for high-throughput screening. Over time, it became clear that more thought in the design phase of library...
Published March 3rd 2008 by CRC Press
The development of parallel synthesis and high-throughput characterization tools offer scientists a time-efficient and cost-effective solution for accelerating traditional synthesis processes and developing the structure-property relationships of multiple materials under variable conditions....
Published July 18th 2006 by CRC Press
Traditionally, the search for new compounds from natural products has been a time- and resource-intensive process. The recent application of combinatorial methods and high-throughput synthesis has allowed scientists to generate a range of new molecular structures from natural products and observe...
Published May 15th 2006 by CRC Press
This volume summarizes most analytical technologies that are applied to solving various problems in broad areas of combinatorial chemistry: chemistry optimization, library synthesis, lead selection, and lead optimization. It also suggests many avenues for further research, especially the need for...
Published January 4th 2000 by CRC Press