New and Published Books
1-10 of 43 results in Handbooks in Pharmacology and Toxicology
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PARP as a Therapeutic Target
Series: Handbooks in Pharmacology and Toxicology
Recent research in cell death mechanisms has rekindled interest in PARP's (Poly (ADP-Ribose) Polymerase) intriguing role in necrosis and apoptosis. While the details of how PARP1 functions are still being elucidated, it has tremendous potential as a promising drug target. PARP inhibitors' dual...
Published March 5th 2002 by CRC Press
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Molecular Bases of Anesthesia
Series: Handbooks in Pharmacology and Toxicology
Molecular Bases of Anesthesia provides a clear overview of the state of knowledge about anesthetic mechanisms at the molecular level of occurrence and focusing on the latest state-of-the-art techniques that relate to how anesthetic drugs cause unconsciousness. With contributions by leading experts,...
Published December 27th 2000 by CRC Press
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Biomedical Applications of Computer Modeling
Series: Handbooks in Pharmacology and Toxicology
Up to the last decade or so, most general modeling approaches to the study of molecular components of biological responses have required significant amount of computer time, expertise, and resources, as well as highly specialized and often custom-written programs. With Biomedical Applications of...
Published September 18th 2000 by CRC Press
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Neurotransmitter Receptors in Actions of Antipsychotic Medications
Series: Handbooks in Pharmacology and Toxicology
Years of extensive investigation into neurophysiology, neurochemistry, and behavioral pharmacology have produced an understanding of antipsychotic medication action that is much more refined than the original dopamine hypothesis. New perspectives offer an array of novel drugs - drugs that pose a...
Published June 21st 2000 by CRC Press
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Cell Death
The Role of PARP
Series: Handbooks in Pharmacology and Toxicology
Poly (ADP-ribose) polymerase (PARP), also termed poly (ADP-ribose) synthetase (PARS) is a nuclear enzyme with a wide range of functions, including regulation of DNA repair, cell differentiation, and gene expression. More than a decade after the identification of PARP-like enzymatic activities in...
Published June 21st 2000 by CRC Press
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Handbook of Alcoholism
Series: Handbooks in Pharmacology and Toxicology
While the war on drugs continues to attract world attention, it is often overlooked that alcoholism remains a major worldwide health concern. No matter what your expertise, the CRC Handbook of Alcoholism can help you acquire the necessary skills to treat problem drinkers and alcohol-dependent...
Published March 23rd 2000 by CRC Press
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Manual of Immunological Methods
Series: Handbooks in Pharmacology and Toxicology
The Manual of Immunological Methods represents the collaboration of the Canadian Network of Toxicology Centers, a non-profit network of university-based scientists dedicated to research, training, risk assessment, and communication. This manual provides detailed immunological methods that can be...
Published July 1st 1998 by CRC Press
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Infectious Diseases in Immunocompromised Hosts
Series: Handbooks in Pharmacology and Toxicology
Because of limited access to medical libraries and medical journals, the majority of clinicians may find it difficult to keep informed on the latest developments in drug manufacture and treatment of infectious diseases in immunocompromised patients. This new handbook strives to fulfill the need for...
Published December 28th 1997 by CRC Press
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Pharmacology of Antimuscarinic Agents
Series: Handbooks in Pharmacology and Toxicology
The theoretical and practical significance of antimuscarinic drugs is more obvious today than ever before. Antimuscarinics have helped to explore the pathomechanisms of of Alzheimer's disease, and to treat the symptoms of Parkinson's, cardiovascular problems, gastrointestinal diseases, and even...
Published November 24th 1997 by CRC Press
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Anabolic Treatments for Osteoporosis
Series: Handbooks in Pharmacology and Toxicology
Osteoporosis, a growing epidemic among women in North America, Europe, and Japan, is a painful, costly disease that has presented a treatment challenge to healthcare professionals. Until recently, therapies have focused on agents that slow bone resorption, and have had only limited success at...
Published October 19th 1997 by CRC Press