New and Published Books
21-30 of 72 results in Chapman & Hall/CRC Biostatistics Series
With Applications in R
In longitudinal studies it is often of interest to investigate how a marker that is repeatedly measured in time is associated with a time to an event of interest, e.g., prostate cancer studies where longitudinal PSA level measurements are collected in conjunction with the time-to-recurrence. Joint...
Published June 21st 2012 by Chapman and Hall/CRC
The emergence of high-speed computing has facilitated the development of many exciting statistical and mathematical methods in the last 25 years, broadening the landscape of available tools in statistical investigations of complex data. Biostatistics: A Computing Approach focuses on visualization...
Published December 19th 2011 by Chapman and Hall/CRC
Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable and non-implantable devices, rehabilitation, psychotherapy, and behavioral interventions. Unlike pharmacological treatments, these have no specific requirements for approval....
Published December 18th 2011 by Chapman and Hall/CRC
With new statistical and scientific issues arising in adaptive clinical trial design, including the U.S. FDA’s recent draft guidance, a new edition of one of the first books on the topic is needed. Adaptive Design Methods in Clinical Trials, Second Edition reflects recent developments and...
Published November 30th 2011 by Chapman and Hall/CRC
An Excel GUI for WinBUGS
Although the popularity of the Bayesian approach to statistics has been growing for years, many still think of it as somewhat esoteric, not focused on practical issues, or generally too difficult to understand. Bayesian Analysis Made Simple is aimed at those who wish to apply Bayesian methods but...
Published August 25th 2011 by Chapman and Hall/CRC
Useful in many areas of medicine and biology, Bayesian methods are particularly attractive tools for the design of clinical trials and diagnostic tests, which are based on established information, usually from related previous studies. Advanced Bayesian Methods for Medical Test Accuracy begins with...
Published July 31st 2011 by CRC Press
Topics in ROC Analysis
Statistical evaluation of diagnostic performance in general and Receiver Operating Characteristic (ROC) analysis in particular are important for assessing the performance of medical tests and statistical classifiers, as well as for evaluating predictive models or algorithms. This book presents...
Published July 26th 2011 by Chapman and Hall/CRC
The increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies. Using examples from real clinical trials, Design and Analysis of Non-Inferiority Trials brings together this body of research and confronts the...
Published July 11th 2011 by Chapman and Hall/CRC
In clinical trial practice, controversial statistical issues inevitably occur regardless of the compliance with good statistical practice and good clinical practice. But by identifying the causes of the issues and correcting them, the study objectives of clinical trials can be better achieved....
Published June 14th 2011 by Chapman and Hall/CRC
As clinicians begin to realize the important role of dose-finding in the drug development process, there is an increasing openness to "novel" methods proposed in the past two decades. In particular, the Continual Reassessment Method (CRM) and its variations have drawn much attention in the medical...
Published March 28th 2011 by Chapman and Hall/CRC
Adaptive Design Theory and Implementation Using SAS and R, Second Edition
To Be Published December 4th 2014
Noninferiority Testing in Clinical Trials: Issues and Challenges
To Be Published December 5th 2014
Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting
To Be Published December 9th 2014
Inference Principles for Biostatisticians
To Be Published December 10th 2014
Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research
To Be Published December 30th 2014
Statistical Methods in Drug Combination Studies
To Be Published January 5th 2015
Design and Analysis of Clinical Trials for Predictive Medicine
To Be Published March 24th 2015
Adaptive Designs for Sequential Treatment Allocation
To Be Published April 15th 2015
Statistical Design and Analysis of Clinical Trials: Principles and Methods
To Be Published May 15th 2015
Clinical Trial Simulations
To Be Published May 25th 2015