New and Published Books
21-30 of 78 results in Chapman & Hall/CRC Biostatistics Series
Design and Analysis of Follow-on Biologics
As many biological products face losing their patents in the next decade, the pharmaceutical industry needs an abbreviated regulatory pathway for approval of biosimilar drug products, which are cost-effective, follow-on/subsequent versions of the innovator’s biologic products. But scientific...
Published July 29th 2013 by Chapman and Hall/CRC
Optimal Design for Nonlinear Response Models discusses the theory and applications of model-based experimental design with a strong emphasis on biopharmaceutical studies. The book draws on the authors’ many years of experience in academia and the pharmaceutical industry. While the focus is on...
Published July 15th 2013 by CRC Press
Using real data sets throughout, Survival Analysis in Medicine and Genetics introduces the latest methods for analyzing high-dimensional survival data. It provides thorough coverage of recent statistical developments in the medical and genetics fields. The text mainly addresses special concerns...
Published June 4th 2013 by Chapman and Hall/CRC
In biostatistical research and courses, practitioners and students often lack a thorough understanding of how to apply statistical methods to synthesize biomedical and clinical trial data. Filling this knowledge gap, Applied Meta-Analysis with R shows how to implement statistical meta-analysis...
Published May 3rd 2013 by Chapman and Hall/CRC
In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of phase II trial results and negative phase III trials...
Published May 2nd 2013 by Chapman and Hall/CRC
Health economics is concerned with the study of the cost-effectiveness of health care interventions. This book provides an overview of Bayesian methods for the analysis of health economic data. After an introduction to the basic economic concepts and methods of evaluation, it presents Bayesian...
Published November 12th 2012 by Chapman and Hall/CRC
Confidence Intervals for Proportions and Related Measures of Effect Size illustrates the use of effect size measures and corresponding confidence intervals as more informative alternatives to the most basic and widely used significance tests. The book provides you with a deep understanding of what...
Published August 25th 2012 by CRC Press
Encyclopedic in breadth, yet practical and concise, Medical Biostatistics, Third Edition focuses on the statistical aspects of medicine with a medical perspective, showing the utility of biostatistics as a tool to manage many medical uncertainties. The author concludes "Just as results of medical...
Published August 7th 2012 by Chapman and Hall/CRC
As the development of medicines has become more globalized, the geographic variations in the efficacy and safety of pharmaceutical products need to be addressed. To accelerate the product development process and shorten approval time, researchers are beginning to design multiregional trials that...
Published July 26th 2012 by Chapman and Hall/CRC
Methods and Applications
Interval-Censored Time-to-Event Data: Methods and Applications collects the most recent techniques, models, and computational tools for interval-censored time-to-event data. Top biostatisticians from academia, biopharmaceutical industries, and government agencies discuss how these advances are...
Published July 19th 2012 by Chapman and Hall/CRC
Introductory Adaptive Trial Designs: A Practical Guide with R
To Be Published June 19th 2015
Statistical Methods for Drug Safety
To Be Published July 7th 2015
Data Analysis with Competing Risks and Intermediate States
To Be Published July 10th 2015
Empirical Likelihood Method in Survival Analysis
To Be Published July 14th 2015
Exposure-Response Modeling: Methods and Practical Implementation
To Be Published July 17th 2015
Statistical Methods for Immunogenicity Assessment
To Be Published July 24th 2015
Modern Adaptive Randomized Clinical Trials: Statistical and Practical Aspects
To Be Published July 29th 2015
Bayesian Methods for Repeated Measures
To Be Published August 18th 2015
Statistical Design and Analysis of Clinical Trials: Principles and Methods
To Be Published August 27th 2015
Dynamical Biostatistical Models
To Be Published September 11th 2015