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Book Series

Chapman & Hall/CRC Biostatistics Series

Series Editor: Shein-Chung Chow, Karl E. Peace, Jen-pei Liu, Byron Jones, Bruce W. Turnbull

New and Published Books

31-40 of 72 results in Chapman & Hall/CRC Biostatistics Series
  1. Design and Analysis of Non-Inferiority Trials

    By Mark D. Rothmann, Brian L. Wiens, Ivan S.F. Chan

    Series: Chapman & Hall/CRC Biostatistics Series

    The increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies. Using examples from real clinical trials, Design and Analysis of Non-Inferiority Trials brings together this body of research and confronts the...

    Published July 12th 2011 by Chapman and Hall/CRC

  2. Controversial Statistical Issues in Clinical Trials

    By Shein-Chung Chow

    Series: Chapman & Hall/CRC Biostatistics Series

    In clinical trial practice, controversial statistical issues inevitably occur regardless of the compliance with good statistical practice and good clinical practice. But by identifying the causes of the issues and correcting them, the study objectives of clinical trials can be better achieved....

    Published June 15th 2011 by Chapman and Hall/CRC

  3. Dose Finding by the Continual Reassessment Method

    By Ying Kuen Cheung

    Series: Chapman & Hall/CRC Biostatistics Series

    As clinicians begin to realize the important role of dose-finding in the drug development process, there is an increasing openness to "novel" methods proposed in the past two decades. In particular, the Continual Reassessment Method (CRM) and its variations have drawn much attention in the medical...

    Published March 29th 2011 by Chapman and Hall/CRC

  4. Measures of Interobserver Agreement and Reliability

    By Mohamed M. Shoukri

    Series: Chapman & Hall/CRC Biostatistics Series

    Agreement among at least two evaluators is an issue of prime importance to statisticians, clinicians, epidemiologists, psychologists, and many other scientists. Measuring interobserver agreement is a method used to evaluate inconsistencies in findings from different evaluators who collect the same...

    Published January 3rd 2011 by CRC Press

  5. Measures of Interobserver Agreement and Reliability, Second Edition

    By Mohamed M. Shoukri

    Series: Chapman & Hall/CRC Biostatistics Series

    Measures of Interobserver Agreement and Reliability, Second Edition covers important issues related to the design and analysis of reliability and agreement studies. It examines factors affecting the degree of measurement errors in reliability generalization studies and characteristics influencing...

    Published December 14th 2010 by CRC Press

  6. Clinical Trial Data Analysis Using R

    By Din Chen, Karl E. Peace

    Series: Chapman & Hall/CRC Biostatistics Series

    Too often in biostatistical research and clinical trials, a knowledge gap exists between developed statistical methods and the applications of these methods. Filling this gap, Clinical Trial Data Analysis Using R provides a thorough presentation of biostatistical analyses of clinical trial data and...

    Published December 14th 2010 by CRC Press

  7. Monte Carlo Simulation for the Pharmaceutical Industry

    Concepts, Algorithms, and Case Studies

    By Mark Chang

    Series: Chapman & Hall/CRC Biostatistics Series

    Helping you become a creative, logical thinker and skillful "simulator," Monte Carlo Simulation for the Pharmaceutical Industry: Concepts, Algorithms, and Case Studies provides broad coverage of the entire drug development process, from drug discovery to preclinical and clinical trial aspects to...

    Published September 29th 2010 by CRC Press

  8. Bayesian Modeling in Bioinformatics

    Edited by Dipak K. Dey, Samiran Ghosh, Bani K. Mallick

    Series: Chapman & Hall/CRC Biostatistics Series

    Bayesian Modeling in Bioinformatics discusses the development and application of Bayesian statistical methods for the analysis of high-throughput bioinformatics data arising from problems in molecular and structural biology and disease-related medical research, such as cancer. It presents a broad...

    Published September 3rd 2010 by Chapman and Hall/CRC

  9. Frailty Models in Survival Analysis

    By Andreas Wienke

    Series: Chapman & Hall/CRC Biostatistics Series

    The concept of frailty offers a convenient way to introduce unobserved heterogeneity and associations into models for survival data. In its simplest form, frailty is an unobserved random proportionality factor that modifies the hazard function of an individual or a group of related individuals....

    Published July 26th 2010 by Chapman and Hall/CRC

  10. Clinical Trial Methodology

    By Karl E. Peace, Ding-Geng (Din) Chen

    Series: Chapman & Hall/CRC Biostatistics Series

    Now viewed as its own scientific discipline, clinical trial methodology encompasses the methods required for the protection of participants in a clinical trial and the methods necessary to provide a valid inference about the objective of the trial. Drawing from the authors’ courses on the subject...

    Published July 20th 2010 by Chapman and Hall/CRC